The Strahle lab at Washington University in St. Louis and Hope Center for Neurological Disorders studies the pathophysiology of hydrocephalus, brain injury and neurodevelopment after intraventricular hemorrhage (IVH)/ germinal matrix hemorrhage. We use a multidisciplinary approach including techniques involving novel imaging, animal models, cell culture and tissue analysis to study the role of iron and ependymal cilia in the pathogenesis of IVH. Please see Strahle Lab website for more info: https://www.strahlelab.com The candidate should be able to assist with developing and conducting research projects, including experiment design, data analysis and documentation of experimental results.
Position Summary: Opening exists for a Post-Doctoral Research Associate and Staff Scientist to join a multidisciplinary lab team to work in the area of neonatal intraventricular hemorrhage.
Primary Duties and Responsibilities: The incumbent will be responsible for performing intracerebroventricular injections in neonatal mice/rats. Will conduct genetic experiments and apply an assortment of molecular biology techniques to critical experiments. Coordinates with collaborators on behavioral and imaging studies. Following instructions and discussions with principal investigator, designs research protocols, including developing procedures for the collection, verification and management of data. Assists in developing and conducting research projects. Assists with grant preparation and reporting. Performs complex statistical analysis of data collected and writes interpretative reports. Verifies the correctness of the data submitted and makes recommendations based on these analyses. Analytical, reasoning and problem-solving skills. Ability to analyze and interpret statistical data and to communicate data in a clear, concise manner. Ability to be a team-player, willingness to learn, good communicator, attention to detail, and to be able to organize data to present work at weekly scheduled lab meetings. Computer literacy including the ability to use a variety of software packages to analyze data. Prepares manuscripts and submits to peer-reviewed journals. Solves practical problems relating to difficulties with equipment or test subjects. Suggests technical or procedural improvements in testing methods. Conducts literature searches related to research project.
Required Qualifications: Ph.D. in neuroscience research accompanied by publication record.
Required Skills: Prior experience in rodent procedures including sample preparation, brain tissue sectioning, IHC, IF, confocal microscopy and cell culture is desired.
Internal Number: 42979
About Strahle Lab, Washington University in Saint Louis
Since 1919, the Washington University Department of Neurosurgery has had a strong tradition of clinical excellence, outstanding research and dynamic teaching. Our mission is to
Provide patients with superior neurosurgical care
Train residents, fellows and scientists so that they can be leaders in the fields of academic neurosurgery and neurosurgical research;
Conduct basic and clinical research to better understand the causes of neurological diseases so that we can apply this knowledge toward better diagnoses and treatments.
Our neurosurgeons provide surgical care at Barnes-Jewish Hospital, ranked 11th in the nation for adult neurology and neurosurgery by U.S. News & World Report in 2014, and at St. Louis Children's Hospital, ranked #5 in the nation by U.S. News for pediatric neurosurgery in 2014-2015. Please see Strahle Lab website for more info: https://www.strahlelab.com